It can be a challenge. SARC can administer the license test verbality to anyone that is vision impaired. Once licensed there are ways you can operate an radio to get on the air. A good resource can be found on a community called BlindHams.com.
ARRL has several articles that can provide some helpful information. Blind Hams Part 1 Part 2
ARRL has a special membership rate for legally blind hams.